During esophageal manometry, a thin, flexible tube containing sensors, known as a catheter, is gently guided through the nose, down the esophagus, and into the stomach. Patients are required to remain still, take slow, smooth breaths, and take small sips of water as the catheter measures the pressure, strength, and pattern of the muscles contracting in the different parts of the esophagus. A computer connected to the catheter records the results, which the physician will review.

This procedure takes approximately 30 minutes, and patients can later resume normal activity.